Description

They are based on the antibacterial activity and pharmacokinetic characteristics of clarithromycin. They take into account both the clinical studies that have been conducted on this drug and its place in the range of currently available antibacterial products. They are limited in adults to infections due to germs defined as sensitive: Documented tonsillitis with beta-hemolytic streptococcus A, as an alternative to treatment with beta-lactams, particularly when this cannot be used. Acute sinusitis. Given the microbiological profile of these infections, macrolides are indicated when treatment with a beta-lactam is not possible. Superinfections of acute bronchitis. Exacerbations of chronic bronchitis. Community-acquired pneumonia in subjects: – without risk factors, – without signs of clinical severity, – in the absence of clinical elements suggestive of a pneumococcal etiology. In case of suspected atypical pneumonia, macrolides are indicated regardless of the severity and the terrain. · Benign skin infections: impetigo, impetiginization of dermatoses, ecthyma, infectious dermohypodermitis (in particular, erysipelas), erythrasma. · Stomatological infections. · For the curative treatment of Mycobacterium avium infections in HIV-infected patients. Official recommendations on the appropriate use of antibacterial agents should be taken into account.